<> "The repository administrator has not yet configured an RDF license."^^ . <> . . "Efforts Towards the Total Synthesis of Amphidinolide B"^^ . "Studies towards the total synthesis of the cytotoxic marine macrolide Amphidinolide B have been disclosed. Catalytic asymmetric AAC methodology has been applied to efficiently generate the C11- and the C18- stereocenters in the requisite fragments 114 and 120 throughƒnbeta-lactones 102 and 81 respectively.An efficient route to install the C14-C15 trisubstituted alkene was realized through a stannylcupration reaction. The Stille and Suzuki cross-coupling methodologies were investigated for the formation of the C13-C15 diene of amphidinolide B. Iodide 90 was coupled with boronic ester 114 via an efficient Suzuki reaction to form a C7-C20 fragment 115. Fragment was further homologated and coupled to sulfone 65 to complete a C1-C20 synthon of amphidinolide B."^^ . "2007-01-29" . . . . . . . . "Apsara"^^ . "Gopalarathnam"^^ . "Apsara Gopalarathnam"^^ . . . . . . "Efforts Towards the Total Synthesis of Amphidinolide B (PDF)"^^ . . . . . . "a_gopalarathnam2006.pdf"^^ . . . "Efforts Towards the Total Synthesis of Amphidinolide B (Indexer Terms)"^^ . . . . . . "indexcodes.txt"^^ . . . "Efforts Towards the Total Synthesis of Amphidinolide B (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "Efforts Towards the Total Synthesis of Amphidinolide B (Other)"^^ . . . . . . "preview.jpg"^^ . . . "Efforts Towards the Total Synthesis of Amphidinolide B (Other)"^^ . . . . . . "medium.jpg"^^ . . . "Efforts Towards the Total Synthesis of Amphidinolide B (Other)"^^ . . . . . . "small.jpg"^^ . . "HTML Summary of #9337 \n\nEfforts Towards the Total Synthesis of Amphidinolide B\n\n" . "text/html" . .