<> "The repository administrator has not yet configured an RDF license."^^ . <> . . "CARBON-CARBON BOND CONSTRUCTION USING ELECTRON TRANSFER INITIATED CYCLIZATION REACTIONS. RUTHENIUM-CATALYZED HYDROESTERIFICATION AND ITS APPLICATION TOWARDS THE SYNTHESIS OF INTEGRAMYCIN"^^ . "Electron transfer initiated cyclization reactions were successfully applied to the construction of carbon-carbon bonds after tuning the chemoselectivity and reactivity of the substrates. Olefins and allenes with several different electron-donating groups served as good nucleophiles in cyclization reactions to generate various carbocycles. Cascade cyclizations involving C-C bond formation also proved to be successful. In most cases, cyclizations gave good to excellent yields with short reaction times. A general protocol has been developed for synthesizing lactones from allylic and homoallylic alcohols using ruthenium-catalyzed hydroesterifications. The lactone synthesis only requires 1-2 steps and can be conducted in one pot. The experimental procedure is simple and the efficiency is considerably improved compared to that of multi-step sequences. Mechanistic studies with deuterium labeling showed that the competition between hydrometalation, β-hydride elimination, and reductive elimination determines the efficiency and regioselectivity of the hydroesterification reactions. Two major fragments of integramycin have been synthesized. The synthesis of the C16-C35 spiroketal unit of integramycin was accomplished in a convergent and stereoselective manner. The sequence includes the usage of a highly efficient ruthenium-mediated hydroesterification reaction. This sequence also demonstrates the efficiency of C,O-dianioic additions into lactones as a method for producing spiroketals in a single operation without recourse to extensive protecting group manipulations. The synthesis of the cis-decalin unit of integramycin was achieved using a cycloaddition and an allylic rearrangement as key steps. The dienyne substrate of the cycloaddition was synthesized enantioselectively in 36% yield over 9 steps. The conditions of the cycloaddition using [(naph)Rh(cod)]SbF6 were optimized and the diastereoselectivity of the cycloaddition was found to be temperature and solvent dependant."^^ . "2005-10-10" . . . . . . . . "Lijun"^^ . "Wang"^^ . "Lijun Wang"^^ . . . . . . "CARBON-CARBON BOND CONSTRUCTION USING ELECTRON TRANSFER INITIATED CYCLIZATION REACTIONS. RUTHENIUM-CATALYZED HYDROESTERIFICATION AND ITS APPLICATION TOWARDS THE SYNTHESIS OF INTEGRAMYCIN (PDF)"^^ . . . . . . "LijunWang2005.pdf"^^ . . . "CARBON-CARBON BOND CONSTRUCTION USING ELECTRON TRANSFER INITIATED CYCLIZATION REACTIONS. RUTHENIUM-CATALYZED HYDROESTERIFICATION AND ITS APPLICATION TOWARDS THE SYNTHESIS OF INTEGRAMYCIN (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "CARBON-CARBON BOND CONSTRUCTION USING ELECTRON TRANSFER INITIATED CYCLIZATION REACTIONS. RUTHENIUM-CATALYZED HYDROESTERIFICATION AND ITS APPLICATION TOWARDS THE SYNTHESIS OF INTEGRAMYCIN (Other)"^^ . . . . . . "preview.jpg"^^ . . . "CARBON-CARBON BOND CONSTRUCTION USING ELECTRON TRANSFER INITIATED CYCLIZATION REACTIONS. RUTHENIUM-CATALYZED HYDROESTERIFICATION AND ITS APPLICATION TOWARDS THE SYNTHESIS OF INTEGRAMYCIN (Other)"^^ . . . . . . "medium.jpg"^^ . . . "CARBON-CARBON BOND CONSTRUCTION USING ELECTRON TRANSFER INITIATED CYCLIZATION REACTIONS. RUTHENIUM-CATALYZED HYDROESTERIFICATION AND ITS APPLICATION TOWARDS THE SYNTHESIS OF INTEGRAMYCIN (Other)"^^ . . . . . . "small.jpg"^^ . . . "CARBON-CARBON BOND CONSTRUCTION USING ELECTRON TRANSFER INITIATED CYCLIZATION REACTIONS. RUTHENIUM-CATALYZED HYDROESTERIFICATION AND ITS APPLICATION TOWARDS THE SYNTHESIS OF INTEGRAMYCIN (Other)"^^ . . . . . . "indexcodes.txt"^^ . . "HTML Summary of #8483 \n\nCARBON-CARBON BOND CONSTRUCTION USING ELECTRON TRANSFER INITIATED CYCLIZATION REACTIONS. RUTHENIUM-CATALYZED HYDROESTERIFICATION AND ITS APPLICATION TOWARDS THE SYNTHESIS OF INTEGRAMYCIN\n\n" . "text/html" . .