<> "The repository administrator has not yet configured an RDF license."^^ . <> . . "New Methods for Heterocycle Preparation"^^ . "This dissertation will describe the development and application of novel methods for heterocycle preparation. The first chapter will outline the development of a titanocene catalyzed epoxide-opening rearrangement to prepare indolines from epoxyanilines. A discussion of the reaction development, along with the substrate scope and limitations will be reported.The second chapter will describe progress toward expanding the scope of aStaudinger/aza-Wittig reaction used to prepare substituted 1,2,4-triazines. This methodology has been applied towards the synthesis of a model system for the DEF rings of the natural product noelaquinone. The challenges associated with the Staudinger/aza-Wittig reaction, and the late-stage oxidation strategy to prepare the DEF rings of the noelaquinone model system will be discussed.The third chapter will describe the importance and general preparation of (E)-alkene peptide isosteres. Using compounds prepared in the UPCMLD and published on PubChem as a reference, we present our ongoing initiative to expand the library of α,β-cyclopropyl-γ-amino acid analogs."^^ . "2011-06-30" . . . . . . . . "John Paul"^^ . "Maciejewski"^^ . "John Paul Maciejewski"^^ . . . . . . "New Methods for Heterocycle Preparation (PDF)"^^ . . . . . . "updated_Maciejewski_JP_PhD_2011_corrected.pdf"^^ . . . "New Methods for Heterocycle Preparation (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "New Methods for Heterocycle Preparation (Other)"^^ . . . . . . "preview.jpg"^^ . . . "New Methods for Heterocycle Preparation (Other)"^^ . . . . . . "medium.jpg"^^ . . . "New Methods for Heterocycle Preparation (Other)"^^ . . . . . . "small.jpg"^^ . . . "New Methods for Heterocycle Preparation (Other)"^^ . . . . . . "indexcodes.txt"^^ . . "HTML Summary of #6660 \n\nNew Methods for Heterocycle Preparation\n\n" . "text/html" . .