relation: http://d-scholarship-dev.library.pitt.edu/29505/ title: The CD8 Antiviral Factor (CAF) can suppress HIV-1 transcription from the Long Terminal Repeat (LTR) promoter in the absence of elements upstream of the CATATAA box creator: Shridhar, V creator: Chen, Y creator: Gupta, P description: Background: The CD8 Antiviral Factor (CAF) suppresses viral transcription from the HIV-1 Long Terminal Repeat (LTR) promoter in a non-cytolytic manner. However, the region on the LTR upon which CAF acts is unknown. Our objective was to determine the region on the LTR upon which CAF acts to suppress HIV-1 transcription. Methods. Serial deletions of the LTR from the 5' end and inactivating point mutations were made. date: 2014-07-21 type: Article type: PeerReviewed format: application/pdf language: en rights: attached identifier: http://d-scholarship-dev.library.pitt.edu/29505/1/art%253A10.1186%252F1743-422X-11-130.pdf format: text/plain language: en rights: attached identifier: http://d-scholarship-dev.library.pitt.edu/29505/7/licence.txt identifier: Shridhar, V and Chen, Y and Gupta, P (2014) The CD8 Antiviral Factor (CAF) can suppress HIV-1 transcription from the Long Terminal Repeat (LTR) promoter in the absence of elements upstream of the CATATAA box. Virology Journal, 11 (1). relation: 10.1186/1743-422X-11-130