eprintid: 25640
rev_number: 18
userid: 1419
dir: disk0/00/02/56/40
datestamp: 2015-07-22 13:15:16
lastmod: 2019-02-02 15:56:56
status_changed: 2015-07-22 13:15:15
type: article
metadata_visibility: show
item_issues_count: 0
eprint_status: archive
creators_name: Wipf, P
creators_name: Coish, PDG
creators_email: pwipf@pitt.edu
creators_email: 
creators_id: PWIPF
creators_id: 
title: Organozirconocene-mediated polyene synthesis: Preparation of asukamycin and manumycin a side chains
ispublished: pub
divisions: sch_as_chemistry
full_text_status: public
abstract: Hydrozirconation of a functionalized alkyne followed by transmetalation and 1,2-addition to α,β-unsaturated aldehydes was used for the syntheses of the eastern side chain of asukamycin and a precursor to the southern side chain common to asukamycin and manumycin A. These routes facilitate analog preparation, and the convergent zirconocene strategy represents an alternative to stepwise Wittig condensations or Stille couplings in polyene synthesis.
date: 1997-07-21
date_type: published
publication: Tetrahedron Letters
volume: 38
number: 29
pagerange: 5073 - 5076
refereed: TRUE
issn: 0040-4039
id_number: 10.1016/S0040-4039(97)01129-5
citation:   Wipf, P and Coish, PDG  (1997) Organozirconocene-mediated polyene synthesis: Preparation of asukamycin and manumycin a side chains.  Tetrahedron Letters, 38 (29).  5073 - 5076.  ISSN 0040-4039     
document_url: http://d-scholarship-dev.library.pitt.edu/25640/1/licence.txt