%0 Journal Article
%@ 0957-4166
%A Iserloh, U
%A Curran, DP
%A Kanemasa, S
%D 1999
%F pittir:22287
%J Tetrahedron Asymmetry
%N 12
%P 2417 - 2428
%T Enantioselective conjugate radical addition reactions mediated by chiral Lewis acid complexes of (R,R)-4,6-dibenzofurandiyl-2,2'-bis(4- phenyloxazoline) (DBFOX/Ph)
%U http://d-scholarship-dev.library.pitt.edu/22287/
%V 10
%X A high-yielding synthesis (50% overall yield) of tridentate bisoxazoline ligand (R,R)-4,6-dibenzofurandiyl-2,2'-bis(4-phenyloxazoline) (DBFOX/Ph) was developed. DBFOX/Ph was subsequently tested in enantioselective conjugate radical additions onto 3-(3-phenyl-2-propenoyl)-2-oxazolidinone. Two dozen Lewis acids were evaluated, and Mg(ClO4)2 emerged as the best Lewis acid in terms of yield and enantioselectivity (100% yield, 75.4% ee (S)).