eprintid: 21376
rev_number: 17
userid: 3453
dir: disk0/00/02/13/76
datestamp: 2014-05-22 19:17:55
lastmod: 2016-11-15 14:19:35
status_changed: 2014-05-22 19:17:55
type: thesis_degree
succeeds: 21373
metadata_visibility: show
contact_email: jiangwt1987@gmail.com
item_issues_id: thesis_degree_versioning
item_issues_id: duplicate_title_21330
item_issues_id: duplicate_title_21372
item_issues_id: duplicate_title_21373
item_issues_type: thesis_degree_versioning
item_issues_type: duplicate_title
item_issues_type: duplicate_title
item_issues_type: duplicate_title
item_issues_description: ETD 21376 is using versioning.
item_issues_description: Duplicate title to <span class="person_name">JIANG, WENTAO</span> <a href="http://d-scholarship.pitt.edu/cgi/users/home?screen=EPrint::View&amp;eprintid=21330"><xhtml:em xmlns:xhtml="http://www.w3.org/1999/xhtml">DEVELOPMENT OF ION MASS SPECTROMETRY-BASED INSTRUMENTATION AND APPLICATIONS.</xhtml:em></a> Master's Thesis, University of Pittsburgh.
item_issues_description: Duplicate title to <span class="person_name">JIANG, WENTAO</span> <a href="http://d-scholarship.pitt.edu/cgi/users/home?screen=EPrint::View&amp;eprintid=21372"><xhtml:em xmlns:xhtml="http://www.w3.org/1999/xhtml">DEVELOPMENT OF ION MASS SPECTROMETRY-BASED INSTRUMENTATION AND APPLICATIONS.</xhtml:em></a> Master's Thesis, University of Pittsburgh.
item_issues_description: Duplicate title to <span class="person_name">JIANG, WENTAO</span> <a href="http://d-scholarship.pitt.edu/cgi/users/home?screen=EPrint::View&amp;eprintid=21373"><xhtml:em xmlns:xhtml="http://www.w3.org/1999/xhtml">DEVELOPMENT OF ION MASS SPECTROMETRY-BASED INSTRUMENTATION AND APPLICATIONS.</xhtml:em></a> Master's Thesis, University of Pittsburgh.
item_issues_timestamp: 2014-04-19 06:23:33
item_issues_timestamp: 2014-04-22 06:24:13
item_issues_timestamp: 2014-04-22 06:24:13
item_issues_timestamp: 2014-04-22 06:24:13
item_issues_status: discovered
item_issues_status: autoresolved
item_issues_status: autoresolved
item_issues_status: autoresolved
item_issues_count: 1
eprint_status: archive
creators_name: JIANG, WENTAO
creators_email: wej10@pitt.edu
creators_id: WEJ10
title: DEVELOPMENT OF ION MASS SPECTROMETRY-BASED INSTRUMENTATION AND APPLICATIONS
ispublished: unpub
divisions: sch_as_chemistry
full_text_status: public
keywords: ion mobility, mass spectrometry, IM-MS, DTIMS, carbon nanotubes, graphene, graphene quantum dots, photo-Fenton reaction, degradation products 
abstract: Ion mobility spectrometry (IMS) is a technique that can rapidly separate ions based on their mobility in an inert buffer gas and provide insights to molecular structure. When coupled with mass spectrometry (MS), IM-MS offers a powerful hybrid analytical technique that has many biological, pharmaceutical, structural, environmental and other applications. During past decades, various types of IM-MS instruments have been built and applied, of which the most popular type is IMS-time of flight (TOF) MS. However, there are biological problems which require resolution higher than TOFMS can provide. The goal of my first project was to build a drift time IMS (DTIMS) and couple it with a commercial linear ion trap (LTQ) mass analyzer which can provide not only quick separation but also mass analysis capability. It can be used for analysis of complex biochemical samples and degradation mixtures for example. Furthermore, the IMS will be subsequently transferred to a LTQ Orbitrap-Velos MS to obtain mass data with high resolution and accuracy. 
The second project focuses on the analysis of carbon nanotube (CNT) and graphene oxide (GO) degradation products using MS. In recent years different methods for carbon nanomaterial deg-radation have been developed and it is of interest to gain better understanding of the degradation process. MS is a suitable analysis method for the detection of intermediate mixtures with mole-cules of different molecular weight size. The objective of this project was to use MS and tandem MS data combined with other analytical techniques (e.g. nuclear magnetic resonance (NMR), Fourier transform infrared spectroscopy (FTIR)) in order to identify and determine the structures of intermediate degradation products of CNT and GO, and understand degradation mechanisms.

date: 2014-05-22
date_type: published
pages: 74
institution: University of Pittsburgh
refereed: TRUE
etdcommittee_type: committee_chair
etdcommittee_type: committee_member
etdcommittee_type: committee_member
etdcommittee_name: Robinson, Renã A. S.
etdcommittee_name: Grabowski, Joseph J.
etdcommittee_name: Star, Alexander
etdcommittee_email: rena@pitt.edu
etdcommittee_email: joeg@pitt.edu
etdcommittee_email: astar@pitt.edu
etdcommittee_id: RENA
etdcommittee_id: JOEG
etdcommittee_id: ASTAR
etd_defense_date: 2014-04-17
etd_approval_date: 2014-05-22
etd_submission_date: 2014-04-15
etd_release_date: 2014-05-22
etd_access_restriction: immediate
etd_patent_pending: FALSE
thesis_type: thesis
degree: MS
citation:   JIANG, WENTAO  (2014) DEVELOPMENT OF ION MASS SPECTROMETRY-BASED INSTRUMENTATION AND APPLICATIONS.  Master's Thesis, University of Pittsburgh.    (Unpublished)  
document_url: http://d-scholarship-dev.library.pitt.edu/21376/1/Thesis_JiangW2.pdf