%A V Lamm
%A X Pan
%A T Taniguchi
%A DP Curran
%J Beilstein Journal of Organic Chemistry
%T Reductions of aldehydes and ketones with a readily available N-heterocyclic carbene borane and acetic acid
%X Acetic acid promotes the reduction of aldehydes and ketones by the readily available N-heterocyclic carbene borane, 1,3-dimethylimidazol-2-ylidene borane. Aldehydes are reduced over 1-24 h at room temperature with 1 equiv of acetic acid and 0.5 equiv of the NHC-borane. Ketone reductions are slower but can be accelerated by using 5 equiv of acetic acid. Aldehydes can be selectively reduced in the presence of ketones. On a small scale, products are isolated by evaporation of the reaction mixture and direct chromatography. ? 2013 Lamm et al.
%P 675 - 680
%V 9
%D 2013
%R 10.3762/bjoc.9.76
%L pittir20682