TY  - JOUR
ID  - pittir20682
UR  - http://d-scholarship-dev.library.pitt.edu/20682/
A1  - Lamm, V
A1  - Pan, X
A1  - Taniguchi, T
A1  - Curran, DP
Y1  - 2013/04/08/
N2  - Acetic acid promotes the reduction of aldehydes and ketones by the readily available N-heterocyclic carbene borane, 1,3-dimethylimidazol-2-ylidene borane. Aldehydes are reduced over 1-24 h at room temperature with 1 equiv of acetic acid and 0.5 equiv of the NHC-borane. Ketone reductions are slower but can be accelerated by using 5 equiv of acetic acid. Aldehydes can be selectively reduced in the presence of ketones. On a small scale, products are isolated by evaporation of the reaction mixture and direct chromatography. © 2013 Lamm et al.
JF  - Beilstein Journal of Organic Chemistry
VL  - 9
TI  - Reductions of aldehydes and ketones with a readily available N-heterocyclic carbene borane and acetic acid
SP  - 675 
AV  - public
EP  -  680
ER  -