relation: http://d-scholarship-dev.library.pitt.edu/20682/
title: Reductions of aldehydes and ketones with a readily available N-heterocyclic carbene borane and acetic acid
creator: Lamm, V
creator: Pan, X
creator: Taniguchi, T
creator: Curran, DP
description: Acetic acid promotes the reduction of aldehydes and ketones by the readily available N-heterocyclic carbene borane, 1,3-dimethylimidazol-2-ylidene borane. Aldehydes are reduced over 1-24 h at room temperature with 1 equiv of acetic acid and 0.5 equiv of the NHC-borane. Ketone reductions are slower but can be accelerated by using 5 equiv of acetic acid. Aldehydes can be selectively reduced in the presence of ketones. On a small scale, products are isolated by evaporation of the reaction mixture and direct chromatography. © 2013 Lamm et al.
date: 2013-04-08
type: Article
type: PeerReviewed
format: application/pdf
language: en
rights: attached
identifier: http://d-scholarship-dev.library.pitt.edu/20682/1/Beilstein_Journal_of_Organic_Chemistry_09-675.pdf
format: text/plain
language: en
rights: attached
identifier: http://d-scholarship-dev.library.pitt.edu/20682/8/licence.txt
identifier:   Lamm, V and Pan, X and Taniguchi, T and Curran, DP  (2013) Reductions of aldehydes and ketones with a readily available N-heterocyclic carbene borane and acetic acid.  Beilstein Journal of Organic Chemistry, 9.  675 - 680.      
relation: 10.3762/bjoc.9.76