%0 Journal Article %@ 0033-4545 %A Curran, DP %D 2000 %F pittir:20552 %J Pure and Applied Chemistry %N 9 %P 1649 - 1653 %T Fluorous methods for synthesis and separation of organic molecules %U http://d-scholarship-dev.library.pitt.edu/20552/ %V 72 %X Fluorous molecules partition out of an organic phase and into a fluorous (highly fluorinated) phase in a liquid-liquid extraction. New fluorous techniques allow simple yet substantive separations of organic reaction mixtures based on the presence or absence of a fluorous tag. Fluorous-tagged molecules can also be separated from nontagged molecules by solid phase extraction over fluorous reverse-phase silica gel. This technique is ideal for solution-phase parallel synthesis because it allows simple yet substantive separations of organic reaction mixtures.