relation: http://d-scholarship-dev.library.pitt.edu/20544/
title: Total synthesis and stereochemical revision of (+)-aeruginosin 298-A
creator: Wipf, P
creator: Methot, JL
description: (aquation presented) Novel routes toward both enantiomers of the bicyclic proline surrogate 2-carboxy-6-hydroxyoctahydroindole, i.e., Choi, were developed on the basis of the oxidative cyclization of L-tyrosine. Synthesis of the proposed sequence of (+)-aeruginosin 298-A did not provide the natural product. Incorporation of a D-leucine residue, in contrast, led to the total synthesis of this thrombin inhibitor.
date: 2000-12-28
type: Article
type: PeerReviewed
format: text/plain
language: en
rights: attached
identifier: http://d-scholarship-dev.library.pitt.edu/20544/1/licence.txt
identifier:   Wipf, P and Methot, JL  (2000) Total synthesis and stereochemical revision of (+)-aeruginosin 298-A.  Organic Letters, 2 (26).  4213 - 4216.  ISSN 1523-7060     
relation: 10.1021/ol006759x