%A P Wipf
%A X Wang
%J Organic Letters
%T A New Ligand Scaffold for Catalytic Asymmetric Alkylzinc Additions to Aldehydes
%X matrix presented 1,3-Azole derivatives of 2-aminocyclohexanecarboxylic acid represent a new class of bidentate ligands for metal-mediated catalytic asymmetric synthesis. N-[2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)cyclohexyl]methanesulfonamide (6) is particularly well suited for the addition of alkylzinc reagents to aliphatic aldehydes in high enantiomeric excess.
%N 7
%P 1197 - 1199
%V 4
%D 2002
%R 10.1021/ol025600c
%L pittir20456