%0 Journal Article %@ 1523-7060 %A Wipf, P %A Soth, MJ %D 2002 %F pittir:20448 %J Organic Letters %N 10 %P 1787 - 1790 %T Synthesis of the C(1)-C(18) segment of lophotoxin and pukalide. Control of 2-alkenylfuran (E/Z)-configuration %U http://d-scholarship-dev.library.pitt.edu/20448/ %V 4 %X Matrix presented The convergent synthesis of the fully functionalized C(1)-C(18) segment 24 of the furanocembranes lophotoxin and pukalide was accomplished in 11 steps and 10% overall yield. The key step was a stereoselective conversion of alkynoate 21 to trimethylsilyl 2-alkenylfuran 22.