%0 Journal Article %@ 1523-7060 %A Matsugi, M %A Curran, DP %D 2004 %F pittir:19869 %J Organic Letters %N 16 %P 2717 - 2720 %T Reverse fluorous solid-phase extraction: A new technique for rapid separation of fluorous compounds %U http://d-scholarship-dev.library.pitt.edu/19869/ %V 6 %X Fluorous-tagged compounds can rapidly be separated from organic (non-tagged) compounds by the new separation technique of reverse fluorous solid-phase extraction (r-fspe). In a reversal of the roles of solid and liquid phases in standard fluorous spe, a mixture is charged to a polar solid phase (standard silica gel) and then eluted with a fluorous solvent or solvent mixture. The organic components of the mixture are retained, while the fluorous components pass.