eprintid: 19807
rev_number: 13
userid: 1419
dir: disk0/00/01/98/07
datestamp: 2013-10-09 16:03:53
lastmod: 2017-10-13 17:55:26
status_changed: 2013-10-09 16:03:53
type: article
metadata_visibility: show
item_issues_count: 0
eprint_status: archive
creators_name: Pierce, JG
creators_name: Waller, DL
creators_name: Wipf, P
creators_email: 
creators_email: 
creators_email: pwipf@pitt.edu
creators_id: 
creators_id: 
creators_id: PWIPF
title: Synthesis of functionalized isoindolinones: Addition of in situ generated organoalanes to acyliminium ions
ispublished: pub
divisions: sch_as_chemistry
full_text_status: public
abstract: Addition of in situ generated di- or trisubstituted alkenylalanes to N-acyliminium ions provides rapid access to functionalized isoindolinones. Subsequent ring closing metathesis leads to tricyclic products. These transformations proceed under mild conditions and allow for the convergent synthesis of biologically significant scaffolds from readily available starting materials.{A figure is presented}. © 2007 Elsevier B.V. All rights reserved.
date: 2007-10-01
date_type: published
publication: Journal of Organometallic Chemistry
volume: 692
number: 21
pagerange: 4618 - 4629
refereed: TRUE
issn: 0022-328X
id_number: 10.1016/j.jorganchem.2007.05.035
pmcid: PMC2726970
pmid: 19684878
citation:   Pierce, JG and Waller, DL and Wipf, P  (2007) Synthesis of functionalized isoindolinones: Addition of in situ generated organoalanes to acyliminium ions.  Journal of Organometallic Chemistry, 692 (21).  4618 - 4629.  ISSN 0022-328X     
document_url: http://d-scholarship-dev.library.pitt.edu/19807/1/licence.txt