eprintid: 19531
rev_number: 12
userid: 1418
dir: disk0/00/01/95/31
datestamp: 2013-08-07 14:48:18
lastmod: 2017-10-15 06:55:26
status_changed: 2013-08-07 14:48:18
type: article
metadata_visibility: show
item_issues_count: 0
eprint_status: archive
creators_name: Kangani, CO
creators_name: Brückner, AM
creators_name: Curran, DP
creators_email: 
creators_email: 
creators_email: curran@pitt.edu
creators_id: 
creators_id: 
creators_id: CURRAN
title: Ring-closing metathesis approach to dictyostatin
ispublished: pub
divisions: sch_as_chemistry
full_text_status: public
abstract: (Chemical Equation Presented) An esterification/ring-closing metathesis approach to dictyostatin and discodermolide is introduced. The approach provides for facile fragment coupling of two main segments of these natural products at the C10-C11 alkene with high to complete Z-selectivity.
date: 2005-02-03
date_type: published
publication: Organic Letters
volume: 7
number: 3
pagerange: 379 - 382
refereed: TRUE
issn: 1523-7060
id_number: 10.1021/ol0478279
pmid: 15673244
mesh_headings: Alkanes--chemistry
mesh_headings: Carbamates--chemistry
mesh_headings: Esters--chemistry
mesh_headings: Indicators and Reagents
mesh_headings: Lactones--chemistry
mesh_headings: Macrolides--chemical synthesis
mesh_headings: Molecular Conformation
mesh_headings: Oxidation-Reduction
mesh_headings: Pyrones--chemistry
mesh_headings: Structure-Activity Relationship
chemical_names: Alkanes
chemical_names: Carbamates
chemical_names: Esters
chemical_names: Indicators and Reagents
chemical_names: Lactones
chemical_names: Macrolides
chemical_names: Pyrones
chemical_names: dictyostatin
chemical_names: discodermolide
citation:   Kangani, CO and Brückner, AM and Curran, DP  (2005) Ring-closing metathesis approach to dictyostatin.  Organic Letters, 7 (3).  379 - 382.  ISSN 1523-7060     
document_url: http://d-scholarship-dev.library.pitt.edu/19531/1/licence.txt