?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.relation=http%3A%2F%2Fd-scholarship-dev.library.pitt.edu%2F19485%2F&rft.title=DEVELOPMENT+OF+PEPTIDE-BASED+METHODS+FOR+CONTROLLING+THE+STRUCTURES%2C+COMPOSITIONS%2C+AND+PROPERTIES+OF+COMPLEX%0D%0ANANOPARTICLE+SUPERSTRUCTURES&rft.creator=Song%2C+Chengyi&rft.description=This+dissertation+describes+the+development+of+a+nanoparticle+assembly+methodology+based+on+the+use+of+peptide+conjugate+molecules.+The+aim+of+this+research+was+to+explore+how+this+methodology+could+be+used+to+control+the+structure%2C+metrics%2C+and+properties+of+product+nanoparticle+superstructures.%0D%0A%0D%0ASpecifically%2C+this+document+describes+mechanistic+studies+aimed+at+understanding+the+key+factors+that+govern+the+nanoparticle+synthesis+and+assembly+process.+Using+what+we+learned+from+these+studies%2C+we+prepared+high-quality+helical+nanoparticle+superstructures+and+studied+their+chirooptical+properties.+We+coupled+theory+and+experiment+to+show+how+tuning+the+metrics+and+structure+of+the+helices+results+in+predictable+and+tailorable+circular+dichroism+(CD)+properties.++We+also+describe+how+the+composition+of+the+peptide+conjugate+can+influence+both+the+structure+of+the+nanoparticle+assembly+and+detail+how+peptide+conjugates+can+be+utilized+to+prepare+%E2%80%98hollow%E2%80%99+sub-100nm+gold+nanoparticle+spheres.++Finally%2C+to+expand+the+composition+scope+of+our+newly+developed+methodology%2C+we+present+a+new+cobalt-binding+peptide+conjugate%2C+which+could+be+used+to+direct+the+synthesis+and+assembly+of+hollow+CoPt+nanospherical+superstructures+exhibiting+electrocatalytic+activity+for+methanol+oxidation.%0D%0A&rft.date=2013-09-30&rft.type=University+of+Pittsburgh+ETD&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.language=en&rft.identifier=http%3A%2F%2Fd-scholarship-dev.library.pitt.edu%2F19485%2F1%2FETD_PhD_Thesis_Chengyi_Song_Chem_department_2013.pdf&rft.identifier=++Song%2C+Chengyi++(2013)+DEVELOPMENT+OF+PEPTIDE-BASED+METHODS+FOR+CONTROLLING+THE+STRUCTURES%2C+COMPOSITIONS%2C+AND+PROPERTIES+OF+COMPLEX+NANOPARTICLE+SUPERSTRUCTURES.++Doctoral+Dissertation%2C+University+of+Pittsburgh.++++(Unpublished)++