TY - JOUR ID - pittir19276 UR - http://d-scholarship-dev.library.pitt.edu/19276/ IS - 18 A1 - Keinan, S A1 - Paquette, WD A1 - Skoko, JJ A1 - Beratan, DN A1 - Yang, W A1 - Shinde, S A1 - Johnston, PA A1 - Lazo, JS A1 - Wipf, P Y1 - 2008/10/03/ N2 - Quinoid inhibitors of Cdc25B were designed based on the Linear Combination of Atomic Potentials (LCAP) methodology. In contrast to a published hypothesis, the biological activities and hydrogen peroxide generation in reducing media of three synthetic models did not correlate with the quinone half-wave potential, E1/2. © 2008 The Royal Society of Chemistry. JF - Organic and Biomolecular Chemistry VL - 6 SN - 1477-0520 TI - Computational design, synthesis and biological evaluation of para-quinone-based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B SP - 3256 AV - public EP - 3263 ER -