eprintid: 19252 rev_number: 18 userid: 1419 dir: disk0/00/01/92/52 datestamp: 2013-07-03 15:44:29 lastmod: 2019-02-02 15:57:11 status_changed: 2013-07-03 15:44:29 type: article metadata_visibility: show item_issues_count: 0 eprint_status: archive creators_name: Pierce, JG creators_name: Kasi, D creators_name: Fushimi, M creators_name: Cuzzupe, A creators_name: Wipf, P creators_email: creators_email: creators_email: creators_email: creators_email: pwipf@pitt.edu creators_id: creators_id: creators_id: creators_id: creators_id: PWIPF title: Synthesis of hydroxylated bicyclic amino acids from L-tyrosine: Octahydro-1H-indole carboxylates ispublished: pub divisions: sch_as_chemistry full_text_status: public abstract: (Chemical Equation Presented) A stereoselective approach to polyhydroxylated L-Choi derivatives has been developed. The oxidative cyclization of L-tyrosine was optimized to avoid partial racemization and to allow a more efficient scale-up. © 2008 American Chemical Society. date: 2008-10-03 date_type: published publication: Journal of Organic Chemistry volume: 73 number: 19 pagerange: 7807 - 7810 refereed: TRUE issn: 0022-3263 id_number: 10.1021/jo801552j other_id: NLM NIHMS86316 other_id: NLM PMC2739982 pmcid: PMC2739982 pmid: 18767800 mesh_headings: Amino Acids--chemical synthesis mesh_headings: Amino Acids--chemistry mesh_headings: Bicyclo Compounds--chemical synthesis mesh_headings: Carboxylic Acids--chemistry mesh_headings: Hydroxylation mesh_headings: Indoles--chemistry mesh_headings: Stereoisomerism mesh_headings: Tyrosine--chemistry chemical_names: Amino Acids chemical_names: Bicyclo Compounds chemical_names: Carboxylic Acids chemical_names: Indoles chemical_names: Tyrosine citation: Pierce, JG and Kasi, D and Fushimi, M and Cuzzupe, A and Wipf, P (2008) Synthesis of hydroxylated bicyclic amino acids from L-tyrosine: Octahydro-1H-indole carboxylates. Journal of Organic Chemistry, 73 (19). 7807 - 7810. ISSN 0022-3263 document_url: http://d-scholarship-dev.library.pitt.edu/19252/1/licence.txt