eprintid: 19097
rev_number: 16
userid: 1418
dir: disk0/00/01/90/97
datestamp: 2013-06-25 16:00:32
lastmod: 2019-02-02 15:59:16
status_changed: 2013-06-25 16:00:32
type: article
metadata_visibility: show
item_issues_count: 0
eprint_status: archive
creators_name: Zhang, W
creators_name: Lu, Y
creators_name: Chen, CHT
creators_name: Curran, DP
creators_name: Geib, S
creators_email: 
creators_email: 
creators_email: 
creators_email: curran@pitt.edu
creators_email: geib@pitt.edu
creators_id: 
creators_id: 
creators_id: 
creators_id: CURRAN
creators_id: GEIB
creators_orcid: 
creators_orcid: 
creators_orcid: 
creators_orcid: 
creators_orcid: 0000-0002-9160-7857
title: Fluorous synthesis of hydantoin-, piperazinedione-, and benzodiazepinedione-fused tricyclic and tetracyclic ring systems
ispublished: pub
divisions: sch_as_chemistry
full_text_status: public
abstract: Fluorous proline derivatives generated from one-pot, three-component [3+2] cycloaddition of azomethine ylides are employed in different post-condensation reactions to form hydantoin-, piperazinedione-, and benzodiazepinedione-fused tricyclic and tetracyclic ring systems. High synthetic efficiency is achieved by conducting fast microwave reactions and purification by easy fluorous solid-phase extractions. Methods developed for these novel drug-like heterocyclic compounds can be applied to diversity-oriented library syntheses. © Wiley-VCH Verlag GmbH & Co. KGaA, 2006.
date: 2006-04-28
date_type: published
publication: European Journal of Organic Chemistry
number: 9
pagerange: 2055 - 2059
refereed: TRUE
issn: 1434-193X
id_number: 10.1002/ejoc.200600077
pmcid: PMC2423324
pmid: 18542714
citation:   Zhang, W and Lu, Y and Chen, CHT and Curran, DP and Geib, S  (2006) Fluorous synthesis of hydantoin-, piperazinedione-, and benzodiazepinedione-fused tricyclic and tetracyclic ring systems.  European Journal of Organic Chemistry (9).  2055 - 2059.  ISSN 1434-193X     
document_url: http://d-scholarship-dev.library.pitt.edu/19097/1/licence.txt