TY - JOUR ID - pittir19097 UR - http://d-scholarship-dev.library.pitt.edu/19097/ IS - 9 A1 - Zhang, W A1 - Lu, Y A1 - Chen, CHT A1 - Curran, DP A1 - Geib, S Y1 - 2006/04/28/ N2 - Fluorous proline derivatives generated from one-pot, three-component [3+2] cycloaddition of azomethine ylides are employed in different post-condensation reactions to form hydantoin-, piperazinedione-, and benzodiazepinedione-fused tricyclic and tetracyclic ring systems. High synthetic efficiency is achieved by conducting fast microwave reactions and purification by easy fluorous solid-phase extractions. Methods developed for these novel drug-like heterocyclic compounds can be applied to diversity-oriented library syntheses. © Wiley-VCH Verlag GmbH & Co. KGaA, 2006. JF - European Journal of Organic Chemistry SN - 1434-193X TI - Fluorous synthesis of hydantoin-, piperazinedione-, and benzodiazepinedione-fused tricyclic and tetracyclic ring systems SP - 2055 AV - public EP - 2059 ER -