relation: http://d-scholarship-dev.library.pitt.edu/19097/
title: Fluorous synthesis of hydantoin-, piperazinedione-, and benzodiazepinedione-fused tricyclic and tetracyclic ring systems
creator: Zhang, W
creator: Lu, Y
creator: Chen, CHT
creator: Curran, DP
creator: Geib, S
description: Fluorous proline derivatives generated from one-pot, three-component [3+2] cycloaddition of azomethine ylides are employed in different post-condensation reactions to form hydantoin-, piperazinedione-, and benzodiazepinedione-fused tricyclic and tetracyclic ring systems. High synthetic efficiency is achieved by conducting fast microwave reactions and purification by easy fluorous solid-phase extractions. Methods developed for these novel drug-like heterocyclic compounds can be applied to diversity-oriented library syntheses. © Wiley-VCH Verlag GmbH & Co. KGaA, 2006.
date: 2006-04-28
type: Article
type: PeerReviewed
format: text/plain
language: en
rights: attached
identifier: http://d-scholarship-dev.library.pitt.edu/19097/1/licence.txt
identifier:   Zhang, W and Lu, Y and Chen, CHT and Curran, DP and Geib, S  (2006) Fluorous synthesis of hydantoin-, piperazinedione-, and benzodiazepinedione-fused tricyclic and tetracyclic ring systems.  European Journal of Organic Chemistry (9).  2055 - 2059.  ISSN 1434-193X     
relation: 10.1002/ejoc.200600077