relation: http://d-scholarship-dev.library.pitt.edu/18573/
title: Selective synthesis of (2Z,4E)-dienyl esters by ene-diene cross metathesis
creator: Moura-Letts, G
creator: Curran, DP
description: (Chemical Equation Presented) Cross metathesis of terminal alkenes with methyl (2Z4E)-hexadienoate and related dienyl esters provides substituted (2Z,4E)-dienyl esters in good yields. Small-scale reactions are effectively promoted by the standard second-generation Grubbs-Hoveyda catalyst (GH-II), while a new fluorous GH-II catalyst is used for separation and recovery in gram-scale reactions. The transformation is featured in a rapid synthesis of the bottom fragments of the potent anticancer agents (-)-dictyostatin and 6-epi-dictyostatin. © 2007 American Chemical Society.
date: 2007-01-04
type: Article
type: PeerReviewed
format: text/plain
language: en
rights: attached
identifier: http://d-scholarship-dev.library.pitt.edu/18573/1/licence.txt
identifier:   Moura-Letts, G and Curran, DP  (2007) Selective synthesis of (2Z,4E)-dienyl esters by ene-diene cross metathesis.  Organic Letters, 9 (1).  5 - 8.  ISSN 1523-7060     
relation: 10.1021/ol062017d