%A X Wang
%A SG Nelson
%A DP Curran
%J Tetrahedron
%T The azido acid approach to ?-peptides: parallel synthesis of a tri-?-peptide library by fluorous tagging
%X A small tri-?-peptide library was prepared starting from three enantio- and diastereopure azido acids. Fluorous tagging followed by two cycles of azide reduction, fluorous solid phase extraction (f-SPE), peptide coupling with the original azido acids, and f-SPE provided 27 protected azido peptides. Reduction and HPLC purification provided 25 of the 27 targeted tri-?-peptides in acceptable yields and excellent purities. ? 2007 Elsevier Ltd. All rights reserved.
%N 27
%P 6141 - 6145
%V 63
%D 2007
%R 10.1016/j.tet.2007.03.034
%L pittir18566