%0 Journal Article
%@ 0040-4020
%A Wang, X
%A Nelson, SG
%A Curran, DP
%D 2007
%F pittir:18566
%J Tetrahedron
%N 27
%P 6141 - 6145
%T The azido acid approach to β-peptides: parallel synthesis of a tri-β-peptide library by fluorous tagging
%U http://d-scholarship-dev.library.pitt.edu/18566/
%V 63
%X A small tri-β-peptide library was prepared starting from three enantio- and diastereopure azido acids. Fluorous tagging followed by two cycles of azide reduction, fluorous solid phase extraction (f-SPE), peptide coupling with the original azido acids, and f-SPE provided 27 protected azido peptides. Reduction and HPLC purification provided 25 of the 27 targeted tri-β-peptides in acceptable yields and excellent purities. © 2007 Elsevier Ltd. All rights reserved.