@article{pittir18566, volume = {63}, number = {27}, month = {July}, author = {X Wang and SG Nelson and DP Curran}, title = {The azido acid approach to {\ensuremath{\beta}}-peptides: parallel synthesis of a tri-{\ensuremath{\beta}}-peptide library by fluorous tagging}, journal = {Tetrahedron}, pages = {6141 -- 6145}, year = {2007}, url = {http://d-scholarship-dev.library.pitt.edu/18566/}, abstract = {A small tri-{\ensuremath{\beta}}-peptide library was prepared starting from three enantio- and diastereopure azido acids. Fluorous tagging followed by two cycles of azide reduction, fluorous solid phase extraction (f-SPE), peptide coupling with the original azido acids, and f-SPE provided 27 protected azido peptides. Reduction and HPLC purification provided 25 of the 27 targeted tri-{\ensuremath{\beta}}-peptides in acceptable yields and excellent purities. {\copyright} 2007 Elsevier Ltd. All rights reserved.} }