?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.relation=http%3A%2F%2Fd-scholarship-dev.library.pitt.edu%2F18466%2F&rft.title=Study+of+Intermediate+Oxidation+Products+in+Chemical+and+Enzymatic+Degradation+of+Carbon+Nanomaterials&rft.creator=Bai%2C+Hao&rft.description=With+increasing+applications+of+carbon+nanomaterials%2C+toxicity+of+the+material+itself+and+the+degradation+products+in+biological+systems+and+environment+becomes+a+valid+concern.+At+present%2C+most+of+the+toxicity+studies+only+focus+on+the+bulk+property+of+carbon+nanomaterials+and+the+relevant+conclusions+are+ambiguous.+To+better+understand+the+degradation+mechanism+and+the+potential+source+of+toxicity%2C+we+separated+the+oxidation+products+and+studied+the+%E2%80%9Csmall+molecules%E2%80%9D+and+%E2%80%9Clarge+particles%E2%80%9D+respectively+in+detail.+In+the+first+oxidation+method%2C+graphene+oxide+was+degraded+by+Fenton+reagent+(Fe2%2B%2FFe3%2B%2FH2O2)+under+UV+irradiation.+Through+techniques+including+mass+spectrometry%2C+nuclear+magnetic+resonance+and+liquid+chromatography%2C+we+successfully+proposed+plausible+product+structures+and+discovered+several+structure+patterns+of+the+products.+By+using+atomic+force+microscopy+and+fluorimeter%2C+we+monitored+the+morphology+transformation+of+graphene+oxide+flakes+(~+600+nm+%C3%97+1+nm)+to+graphene+quantum+dots+(~+25+nm+%C3%97+5+nm)%2C+in+both+aqueous+solution+and+immobilized+system.+Given+the+similarity+of+Fenton+reagent+chemical+oxidation+and+horseradish+peroxidase+enzymatic+degradation+of+carbon+nanomaterials%2C+our+results+will+help+to+understand+the+enzymatic+degradation+mechanism+in+biosystem+and+in+the+environment+and+to+assess+the+toxicity+at+different+stages+during+the+degradation+process.+In+the+second+part%2C+we+studied+the+degradation+of+SWNTs+in+both+MPO+and+NaClO+systems+and+further+optimization+is+required+to+eliminate+the+ion+suppression+resulting+from+the+high+concentration+of+salt+in+these+systems.+&rft.date=2013-07-24&rft.type=University+of+Pittsburgh+ETD&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.language=en&rft.identifier=http%3A%2F%2Fd-scholarship-dev.library.pitt.edu%2F18466%2F1%2FThesis_Hao_Bai_3rd.pdf&rft.identifier=++Bai%2C+Hao++(2013)+Study+of+Intermediate+Oxidation+Products+in+Chemical+and+Enzymatic+Degradation+of+Carbon+Nanomaterials.++Master's+Thesis%2C+University+of+Pittsburgh.++++(Unpublished)++