relation: http://d-scholarship-dev.library.pitt.edu/18198/
title: Amide bond formation with a new fluorous carbodiimide: Separation by reverse fluorous solid-phase extraction
creator: Del Pozo, C
creator: Keller, AI
creator: Nagashima, T
creator: Curran, DP
description: A new fluorous carbodiimide is introduced along with a convenient procedure for amide coupling reactions. Reactions of acids and amines under standard conditions for carbodiimide couplings, followed by simple reverse fluorous solid-phase extraction (FSPE) over standard silica gel, provide the target amide products in good yields and purities. The use of HFE-7100 as a fluorous solvent is crucial for the success of the reverse FSPE. © 2007 American Chemical Society.
date: 2007-10-11
type: Article
type: PeerReviewed
format: text/plain
language: en
rights: attached
identifier: http://d-scholarship-dev.library.pitt.edu/18198/1/licence.txt
identifier:   Del Pozo, C and Keller, AI and Nagashima, T and Curran, DP  (2007) Amide bond formation with a new fluorous carbodiimide: Separation by reverse fluorous solid-phase extraction.  Organic Letters, 9 (21).  4167 - 4170.  ISSN 1523-7060     
relation: 10.1021/ol701631m