@article{pittir18198, volume = {9}, number = {21}, month = {October}, author = {C Del Pozo and AI Keller and T Nagashima and DP Curran}, title = {Amide bond formation with a new fluorous carbodiimide: Separation by reverse fluorous solid-phase extraction}, journal = {Organic Letters}, pages = {4167 -- 4170}, year = {2007}, url = {http://d-scholarship-dev.library.pitt.edu/18198/}, abstract = {A new fluorous carbodiimide is introduced along with a convenient procedure for amide coupling reactions. Reactions of acids and amines under standard conditions for carbodiimide couplings, followed by simple reverse fluorous solid-phase extraction (FSPE) over standard silica gel, provide the target amide products in good yields and purities. The use of HFE-7100 as a fluorous solvent is crucial for the success of the reverse FSPE. {\copyright} 2007 American Chemical Society.} }