eprintid: 18101
rev_number: 16
userid: 1418
dir: disk0/00/01/81/01
datestamp: 2013-04-08 17:20:28
lastmod: 2019-02-02 15:59:16
status_changed: 2013-04-08 17:20:28
type: article
metadata_visibility: show
item_issues_count: 0
eprint_status: archive
creators_name: Jung, WH
creators_name: Guyenne, S
creators_name: Riesco-Fagundo, C
creators_name: Mancuso, J
creators_name: Nakamura, S
creators_name: Curran, DP
creators_email: 
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creators_email: curran@pitt.edu
creators_id: 
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creators_id: CURRAN
title: Confirmation of the stereostructure of (+)-cytostatin by fluorous mixture synthesis of four candidate stereoisomers
ispublished: pub
divisions: sch_as_chemistry
full_text_status: public
abstract: Mix and match: Four closely related candidate isomers for cytostatin have been synthesized by using the technique of fluorous mixture synthesis. Comparison of NMR, thin-layer chromatography, and optical rotation data enabled the three isomers that were not cytostatin to be identified. Thus, by a process of elimination (disproof), the isomer corresponding to cytostatin was determined, and the 4S,5S,6S,9S,10S,11S configuration confirmed. (Chemical Equation Presented). © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
date: 2008-02-11
date_type: published
publication: Angewandte Chemie - International Edition
volume: 47
number: 6
pagerange: 1130 - 1133
refereed: TRUE
issn: 1433-7851
id_number: 10.1002/anie.200704893
pmid: 18175302
mesh_headings: Fluorine Compounds--chemistry
mesh_headings: Molecular Structure
mesh_headings: Organophosphates--chemical synthesis
mesh_headings: Organophosphates--chemistry
mesh_headings: Pyrones--chemical synthesis
mesh_headings: Pyrones--chemistry
mesh_headings: Stereoisomerism
chemical_names: Fluorine Compounds
chemical_names: Organophosphates
chemical_names: Pyrones
chemical_names: cytostatin
citation:   Jung, WH and Guyenne, S and Riesco-Fagundo, C and Mancuso, J and Nakamura, S and Curran, DP  (2008) Confirmation of the stereostructure of (+)-cytostatin by fluorous mixture synthesis of four candidate stereoisomers.  Angewandte Chemie - International Edition, 47 (6).  1130 - 1133.  ISSN 1433-7851     
document_url: http://d-scholarship-dev.library.pitt.edu/18101/1/licence.txt