<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "Photonic crystal glucose-sensing material for noninvasive monitoring of glucose in tear fluid"^^ . "Background: We recently developed a photonic crystal glucose-sensing material (Alexeev et al., Anal Chem 2003;75:2316-23), which consists of a crystalline colloidal array embedded within a polymer network of a polyacrylamide-poly(ethylene glycol) hydrogel with pendent phenylboronic acid groups. The aim of the present work was to improve this approach for application to noninvasive or minimally invasive monitoring of glucose. Methods: We used new boronic acid derivatives such as 4-amino-3-fluorophenylboronic acid and 4-carboxy-3-fluorophenylboronic acid as the molecular recognition elements to achieve sensing at physiologic pH values. Results: The improved photonic glucose-sensing material sensed glucose in the range of the 100 μmol/L concentrations found in tear fluid. The detection limits were ∼1 μmol/L in synthetic tear fluid. The visually evident diffraction color shifted across the entire visible spectral region from red to blue over the physiologically relevant tear-fluid glucose concentrations. This sensing material is selective for glucose over galactose, mannose, and fructose. Conclusions: These new glucose sensors have properties appropriate for use in such glucose-sensing applications as ocular inserts or diagnostic contact lenses for patients with diabetes mellitus. © 2004 American Association for Clinical Chemistry."^^ . "2004-12-01" . . "50" . "12" . . "Clinical Chemistry"^^ . . . "00099147" . . . . . . . . . . . . . . . . "VL"^^ . "Alexeev"^^ . "VL Alexeev"^^ . . "DN"^^ . "Finegold"^^ . "DN Finegold"^^ . . "SA"^^ . "Asher"^^ . "SA Asher"^^ . . "S"^^ . "Das"^^ . "S Das"^^ . . . . . . "Photonic crystal glucose-sensing material for noninvasive monitoring of glucose in tear fluid (Plain Text)"^^ . . . "licence.txt"^^ . . . "Photonic crystal glucose-sensing material for noninvasive monitoring of glucose in tear fluid (Other)"^^ . . . . . . "indexcodes.txt"^^ . . "HTML Summary of #17189 \n\nPhotonic crystal glucose-sensing material for noninvasive monitoring of glucose in tear fluid\n\n" . "text/html" . .