eprintid: 17156
rev_number: 29
userid: 1419
dir: disk0/00/01/71/56
datestamp: 2013-01-23 21:46:38
lastmod: 2021-06-12 20:55:17
status_changed: 2013-01-23 21:46:38
type: article
metadata_visibility: show
item_issues_count: 0
eprint_status: archive
creators_name: Asher, SA
creators_name: Alexeev, VL
creators_name: Goponenko, AV
creators_name: Sharma, AC
creators_name: Lednev, IK
creators_name: Wilcox, CS
creators_name: Finegold, DN
creators_email: asher@pitt.edu
creators_email: 
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creators_email: 
creators_email: 
creators_email: daylite@pitt.edu
creators_email: 
creators_id: ASHER
creators_id: 
creators_id: 
creators_id: 
creators_id: 
creators_id: DAYLITE
creators_id: 
title: Photonic crystal carbohydrate sensors: Low ionic strength sugar sensing
ispublished: pub
divisions: sch_as_chemistry
full_text_status: public
abstract: We developed a carbohydrate sensing material, which consists of a crystalline colloidal array (CCA) incorporated into a polyacrylamide hydrogel (PCCA) with pendent boronic acid groups. The embedded CCA diffracts visible light, and the PCCA diffraction wavelength reports on the hydrogel volume. This boronic acid PCCA responds to species containing vicinal cis diols such as carbohydrates. This PCCA photonic crystal sensing material responds to glucose in low ionic strength aqueous solutions by swelling and red shifting its diffraction as the glucose concentration increases. The hydrogel swelling results from a Donnan potential due to formation of boronate anion; the boronic acid pKa decreases upon glucose binding. This sensing material responds to glucose and other sugars at <50 μM concentrations in low ionic strength solutions.
date: 2003-03-19
date_type: published
publication: Journal of the American Chemical Society
volume: 125
number: 11
pagerange: 3322 - 3329
refereed: TRUE
issn: 0002-7863
id_number: 10.1021/ja021037h
pmid: 12630888
mesh_headings: Acrylic Resins--chemistry
mesh_headings: Biosensing Techniques--methods
mesh_headings: Boronic Acids--chemistry
mesh_headings: Glucose--analysis
mesh_headings: Hydrogels--chemistry
mesh_headings: Osmolar Concentration
chemical_names: Acrylic Resins
chemical_names: Boronic Acids
chemical_names: Hydrogels
chemical_names: Glucose
chemical_names: polyacrylamide
chemical_names: benzeneboronic acid
citation:   Asher, SA and Alexeev, VL and Goponenko, AV and Sharma, AC and Lednev, IK and Wilcox, CS and Finegold, DN  (2003) Photonic crystal carbohydrate sensors: Low ionic strength sugar sensing.  Journal of the American Chemical Society, 125 (11).  3322 - 3329.  ISSN 0002-7863     
document_url: http://d-scholarship-dev.library.pitt.edu/17156/1/licence.txt