TY  - JOUR
ID  - pittir17156
UR  - http://d-scholarship-dev.library.pitt.edu/17156/
IS  - 11
A1  - Asher, SA
A1  - Alexeev, VL
A1  - Goponenko, AV
A1  - Sharma, AC
A1  - Lednev, IK
A1  - Wilcox, CS
A1  - Finegold, DN
Y1  - 2003/03/19/
N2  - We developed a carbohydrate sensing material, which consists of a crystalline colloidal array (CCA) incorporated into a polyacrylamide hydrogel (PCCA) with pendent boronic acid groups. The embedded CCA diffracts visible light, and the PCCA diffraction wavelength reports on the hydrogel volume. This boronic acid PCCA responds to species containing vicinal cis diols such as carbohydrates. This PCCA photonic crystal sensing material responds to glucose in low ionic strength aqueous solutions by swelling and red shifting its diffraction as the glucose concentration increases. The hydrogel swelling results from a Donnan potential due to formation of boronate anion; the boronic acid pKa decreases upon glucose binding. This sensing material responds to glucose and other sugars at <50 ?M concentrations in low ionic strength solutions.
JF  - Journal of the American Chemical Society
VL  - 125
SN  - 0002-7863
TI  - Photonic crystal carbohydrate sensors: Low ionic strength sugar sensing
SP  - 3322 
AV  - public
EP  -  3329
ER  -