TY  - UNPB
ID  - pittir16753
UR  - http://d-scholarship-dev.library.pitt.edu/16753/
A1  - Buck, Eric
Y1  - 2013/01/25/
N2  - Three routes toward the total synthesis of the neurotoxin anatoxin-a(s) have been explored. They focus on the assembly of the backbone utilizing both Pd(0)- and Pd(II)-mediated processes. Our current route leads to a late-stage precursor of anatoxin-a(s), hydroxy guanidine 134, in 18 steps and in 8.0% overall yield utilizing an amidoalkylation step in the key cyclization.
KW  - anatoxin-a(s)
KW  -  guanidine
KW  -  
TI  - SYNTHETIC STUDIES TOWARDS THE SYNTHESIS OF ANATOXIN-A(S)
EP  - 136
AV  - public
ER  -