<> "The repository administrator has not yet configured an RDF license."^^ . <> . . "Catalytic Asymmetric Bond Constructions in Complex Molecule Synthesis. An Approach to the Synthesis of Spirolide C and the Development of Enantioselective Enolate Hydroxylation Reactions"^^ . "The asymmetric synthesis of spirolide C, a highly potent marine toxin, has been investigated in our laboratory. The construction of C7-C28 bis-spiroketal was completed through a strategy utilizing an intermolecular Stetter reaction and a biomimetic ketalization process. Stereocenters were set in great diastereo- and enantioselectivity via asymmetric catalysis. The efficiency of the synthesis was demonstrated by its convergency and high yields. \r\n\r\nA cinchona alkaloid catalyzed ketene-oxaziridine cyclocondensation has been developed to provide an access to enantioenriched α-hydroxy carbonyl compounds. The oxazolidinones arising from the cyclocondensation were converted to various α-hydroxy carbonyl compounds via nucleophilic ring openings. Greater than 98% ee was achieved in oxazolidinone formation and the subsequent ring openings proceeded with retention of the ee or minor epimerization.\r\n"^^ . "2013-01-25" . . . . . . . . "Binbin"^^ . "Guo"^^ . "Binbin Guo"^^ . . . . . . "Catalytic Asymmetric Bond Constructions in Complex Molecule Synthesis. An Approach to the Synthesis of Spirolide C and the Development of Enantioselective Enolate Hydroxylation Reactions (PDF)"^^ . . . . . . "Binbin_Guo_dissertation.pdf"^^ . . . "Catalytic Asymmetric Bond Constructions in Complex Molecule Synthesis. An Approach to the Synthesis of Spirolide C and the Development of Enantioselective Enolate Hydroxylation Reactions (Indexer Terms)"^^ . . . . . . "indexcodes.txt"^^ . . . "Catalytic Asymmetric Bond Constructions in Complex Molecule Synthesis. An Approach to the Synthesis of Spirolide C and the Development of Enantioselective Enolate Hydroxylation Reactions (Other)"^^ . . . . . . "lightbox.jpg"^^ . . . "Catalytic Asymmetric Bond Constructions in Complex Molecule Synthesis. An Approach to the Synthesis of Spirolide C and the Development of Enantioselective Enolate Hydroxylation Reactions (Other)"^^ . . . . . . "preview.jpg"^^ . . . "Catalytic Asymmetric Bond Constructions in Complex Molecule Synthesis. An Approach to the Synthesis of Spirolide C and the Development of Enantioselective Enolate Hydroxylation Reactions (Other)"^^ . . . . . . "medium.jpg"^^ . . . "Catalytic Asymmetric Bond Constructions in Complex Molecule Synthesis. An Approach to the Synthesis of Spirolide C and the Development of Enantioselective Enolate Hydroxylation Reactions (Other)"^^ . . . . . . "small.jpg"^^ . . "HTML Summary of #16511 \n\nCatalytic Asymmetric Bond Constructions in Complex Molecule Synthesis. An Approach to the Synthesis of Spirolide C and the Development of Enantioselective Enolate Hydroxylation Reactions\n\n" . "text/html" . .