?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.relation=http%3A%2F%2Fd-scholarship-dev.library.pitt.edu%2F10454%2F&rft.title=Advances+in+Materials+Development+of+Responsive+Photonic+Crystal+Hydrogels&rft.creator=Muscatello%2C+Michelle+Marie&rft.description=We+advanced+the+material+development+of+our+responsive+photonic+crystal+hydrogels%2C+which+are+utilized+in+our+polymerized+crystalline+colloidal+array+(PCCA)+technology.+PCCA+consist+of+a+hydrogel+network+that+embeds+an+array+of+monodisperse%2C+highly-charged+100-200+nm+polystyrene+particles.+The+optical+properties+of+the+embedded+array+are+such+that+it+Bragg+diffracts+visible+light.+Responsive+materials+are+fabricated+by+exploiting+the+volume-responsive+nature+of+the+hydrogel+network%2C+such+that+the+material+is+functionalized+to+respond+to+a+specific+analyte+of+interest+by+actuating+a+volume+change+in+the+hydrogel%2C+resulting+in+a+change+in+the+color+of+diffracted+light.We+prepared+a+new+hydrogel+system+for+the+preparation+of+responsive+PCCA+based+on+the+biocompatible+and+rehydratable+polymer+polyvinyl+alcohol+(PVA).+This+material+can+be+reversibly+dehydrated+and+rehydrated%2C+without+the+use+of+fillers%2C+while+retaining+the+diffraction+and+swelling+properties+of+polymerized+crystalline+colloidal+arrays.+This+reversibility+of+rehydration+of+this+new+hydrogel+material+enables+practical+storage+of+hydrogel-based+photonic+crystal+sensors+in+the+dry+state%2C+which+makes+them+much+more+useful+for+future+commercial+applications.We+continued+the+development+of+our+PCCA+glucose+sensing+materials+for+application+in+monitoring+relatively+high+glucose+concentrations%2C+such+as+found+in+blood.+We+modified+our+synthetic+fabrication+methodologies+in+order+to+increase+the+reproducibility+of+our+sensing+materials.+We+advanced+our+understanding+of+the+sensing+response+by+utilizing+independently+determined+variables+in+our+modeling+of+the+PCCA+diffraction+response.+We+characterized+our+material's+response+dependence+upon+environmental+variations+and+interferences.We+completed+the+first+quantitative+study+of+how+the+mechanical+properties+of+a+swollen+hydrogel+depend+upon+the+size+of+nonbonded+embedded+nanoparticles.+We+experimentally+determined+the+dependence+of+the+elastic+shear+storage+modulus+for+our+PCCA%2C+as+a+function+of+embedded+CCA+size+and+prepolymerization+conditions%2C+and+found+that+the+modulus+increases+linearly+with+increasing+CCA+size+due+to+interaction+between+the+embedded+nanoparticles+and+the+hydrogel+matrix.+The+effective+hydrogel+crosslink+densities+determined+from+these+storage+modulus+values+indicate+that+we+can+affect+the+responsivity+of+our+photonic+crystal+materials+by+controlling+the+included+nanoparticle+size.&rft.date=2009-06-17&rft.type=University+of+Pittsburgh+ETD&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.language=en&rft.identifier=http%3A%2F%2Fd-scholarship-dev.library.pitt.edu%2F10454%2F1%2Fmuscatellomm_2008.pdf&rft.identifier=++Muscatello%2C+Michelle+Marie++(2009)+Advances+in+Materials+Development+of+Responsive+Photonic+Crystal+Hydrogels.++Doctoral+Dissertation%2C+University+of+Pittsburgh.++++(Unpublished)++