Fluorous methods for synthesis and separation of organic molecules

Curran, DP (2000) Fluorous methods for synthesis and separation of organic molecules. Pure and Applied Chemistry, 72 (9). 1649 - 1653. ISSN 0033-4545

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Abstract

Fluorous molecules partition out of an organic phase and into a fluorous (highly fluorinated) phase in a liquid-liquid extraction. New fluorous techniques allow simple yet substantive separations of organic reaction mixtures based on the presence or absence of a fluorous tag. Fluorous-tagged molecules can also be separated from nontagged molecules by solid phase extraction over fluorous reverse-phase silica gel. This technique is ideal for solution-phase parallel synthesis because it allows simple yet substantive separations of organic reaction mixtures.

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Details

Item Type:	Article
Status:	Published
Creators/Authors:	Creators Email Pitt Username ORCID Curran, DP curran@pitt.edu CURRAN
Date:	1 January 2000
Date Type:	Publication
Journal or Publication Title:	Pure and Applied Chemistry
Volume:	72
Number:	9
Page Range:	1649 - 1653
DOI or Unique Handle:	10.1351/pac200072091649
Schools and Programs:	Dietrich School of Arts and Sciences > Chemistry
Refereed:	Yes
ISSN:	0033-4545
Date Deposited:	14 Feb 2014 16:49
Last Modified:	02 Feb 2019 15:58
URI:	http://d-scholarship-dev.library.pitt.edu/id/eprint/20552

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