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Total synthesis of (-)-dictyostatin: Confirmation of relative and absolute configurations

Shin, Y and Fournier, JH and Fukui, Y and Brückner, AM and Curran, DP (2004) Total synthesis of (-)-dictyostatin: Confirmation of relative and absolute configurations. Angewandte Chemie - International Edition, 43 (35). 4634 - 4637. ISSN 1433-7851

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Abstract

Will the real dictyostatin please stand up? There were five finalists as stereostructures for the potent anticancer agent dictyostatin; ten, if one were to include enantiomers. A total synthesis of (-)-dictyostatin (1) has ended the decade-old masquerade and identified the winner as a structure recently proposed by Paterson and Wright.

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Details

Item Type: Article
Status: Published
Creators/Authors:
CreatorsEmailPitt UsernameORCID
Shin, Y
Fournier, JH
Fukui, Y
Brückner, AM
Curran, DPcurran@pitt.eduCURRAN
Date: 6 September 2004
Date Type: Publication
Journal or Publication Title: Angewandte Chemie - International Edition
Volume: 43
Number: 35
Page Range: 4634 - 4637
DOI or Unique Handle: 10.1002/anie.200460593
Schools and Programs: Dietrich School of Arts and Sciences > Chemistry
Refereed: Yes
ISSN: 1433-7851
MeSH Headings: Macrolides--chemical synthesis; Macrolides--chemistry; Molecular Conformation
PubMed ID: 15316999
Date Deposited: 18 Oct 2013 17:33
Last Modified: 13 Oct 2017 20:56
URI: http://d-scholarship-dev.library.pitt.edu/id/eprint/19879

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