Total synthesis of luotonin and a small library of AB-ring substituted analogues by cascade radical annulation of isonitriles

Tangirala, R and Antony, S and Agama, K and Pommier, Y and Curran, DP (2005) Total synthesis of luotonin and a small library of AB-ring substituted analogues by cascade radical annulation of isonitriles. Synlett (18). 2843 - 2846. ISSN 0936-5214

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Abstract

A four-step total synthesis of luotonin is deployed to make a small library of AB-ring substituted analogues. These analogues show weak activity in a standard topoisomerase I mediated DNA cleavage assay. © Georg Thieme Verlag Stuttgart.

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Details

Item Type:	Article
Status:	Published
Creators/Authors:	Creators Email Pitt Username ORCID Tangirala, R Antony, S Agama, K Pommier, Y Curran, DP curran@pitt.edu CURRAN
Date:	3 November 2005
Date Type:	Publication
Journal or Publication Title:	Synlett
Number:	18
Page Range:	2843 - 2846
DOI or Unique Handle:	10.1055/s-2005-918923
Schools and Programs:	Dietrich School of Arts and Sciences > Chemistry
Refereed:	Yes
ISSN:	0936-5214
Date Deposited:	15 Jul 2013 19:54
Last Modified:	02 Feb 2019 15:59
URI:	http://d-scholarship-dev.library.pitt.edu/id/eprint/19279

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